Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, also known by its trade name SYN-HYCAN, is a small synthetic tripeptide composed of three amino acids with a molecular weight below 500 Da, which is considered favorable for skin penetration. It is classified as a skin conditioning ingredient under CosIng and carries the CAS number 934368-60-2. The manufacturer positions it as a "needle-free hyaluronan booster" suggested for firming, remodelling, and anti-sagging treatments.
According to manufacturer claims supported by in-vitro tests, it can boost hyaluronic acid synthesis in the skin by up to 300%, contributing to hydration and plumpness. It may also improve collagen fiber quality by increasing structural skin elements (proteoglycans) such as decorin and lumican, supporting skin firmness and remodelling.

