Sodium Hyaluronate Crosspolymer
Sodium Hyaluronate Crosspolymer is a chemically cross-linked form of hyaluronic acid (sodium salt) where normal HA chains (1–2 million Da molecular weight) are bound together to create a large, mesh-like polymer structure. Its CAS number is 105524-32-1 and it is described by CosIng as functioning as a humectant and skin conditioning agent. The cross-linking technology was originally developed for dermal fillers, and this ingredient is the topical counterpart of the FDA-approved dermal filler Hylan B gel.
The cross-linked HA mesh has a water-binding capacity reported to be 5 times greater than that of standard hyaluronic acid, forming a smooth film on skin that continuously delivers moisture for long-term hydration. A 2016 study found that a cross-linked resilient HA reduced trans-epidermal water loss (TEWL) by 27.8%, outperforming both high- and low-molecular-weight HA. The source characterizes it as likely superior to traditional HA versions for moisturizing and barrier support.
