INCI · active · CIR review pending · used in 3 products
Protease
Protease (CAS 9001-92-7, EC 232-642-4, chemical/IUPAC name: Proteinase) is an enzyme that breaks down proteins. In cosmetics it is officially classified under the CosIng function of skin conditioning. It appears frequently in exfoliating cleansing powders, peeling gels, and toners.
Evidence level
weakEWG score
—Comedogenic
—Category
active● Benefits
As a proteolytic enzyme, protease helps break down and remove dead skin cell proteins on the surface, supporting gentle enzymatic exfoliation. Its skin conditioning function is recognized in the official CosIng database.
exfoliatingpore-minimizing
● Cautions
As an enzyme-based exfoliant, it may cause sensitivity in individuals with compromised skin barriers; the source does not list specific cautions.

