INCI · humectant · CIR review pending · used in 8 products
Polyquaternium-51
Polyquaternium-51 (CAS #125275-25-4) is a biocompatible copolymer composed of 2-(n,n,n-trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt polymerized with butyl 2-methyl-2-propenoate. Its structure mimics that of phospholipids, which are key components of cell membranes. It is classified by CosIng as a film-forming and skin-conditioning ingredient.
Evidence level
weakEWG score
—Comedogenic
—Category
humectant● Benefits
Polyquaternium-51 functions as a skin moisturizer and leaves a silky, smooth feel on the skin. It can also help reduce irritation caused by harsh ingredients such as surfactants.
hydratingbarrier-supportsoothingfilm-forming
● Cautions







