Palmitoyl Tripeptide-5
Palmitoyl Tripeptide-5, also known by the trade name Syn-Coll, is the reaction product of palmitic acid and tripeptide-5 (the three-amino-acid sequence Lys-Val-Lys). It is classified as a cell-communicating ingredient and is listed under the official CosIng function of skin conditioning. It is used in a wide range of anti-aging serums, creams, and eye treatments.
Claimed to protect and boost collagen and improve skin texture. Manufacturer-conducted in-vivo studies found that 1% and 2.5% concentrations used twice daily for 84 days reduced the appearance of wrinkles by 7% and 12% respectively; a separate manufacturer study reported that 77% of participants felt it visibly improved firmness and elasticity, and 60% noticed a reduction in the look of pore size after 4 weeks.
Supporting studies cited in the source are manufacturer-conducted, which limits independence and generalizability of the findings.
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