Lactococcus Ferment Lysate
Lactococcus Ferment Lysate is a probiotic-derived ingredient obtained from the Gram-positive bacteria Lactococcus lactis. It is produced by breaking down the cell membrane of the fermentation product, yielding a fluid containing cytoplasm and cell wall fragments. Its official CosIng function is skin conditioning.
According to manufacturer in-vitro data, it stimulates gene expression of proteins that bind live skin cells together (e.g., Occludin, Desmocollin 1, Desmoglein 1) and enzymes involved in shedding dead skin cells, supporting barrier function and natural skin renewal. A small in-vivo study (5 volunteers) found that 3% LFL used twice daily resulted in a thicker stratum corneum and reduced trans-epidermal water loss after 4 days. It also showed stimulation of antimicrobial peptide production, potentially supporting skin immunocompetence.
Evidence is largely manufacturer-conducted in-vitro tests and a single very small in-vivo study (5 volunteers); the source describes it as "promising but fairly unproven."
