Hydrolyzed Hyaluronic Acid

Acts as a humectant to help the skin retain water, contributing to plumpness and elasticity. The 100–300 kDa fraction may support skin self-defense and wound healing, and is noted as particularly suitable for sensitive, acne-prone, or rosacea-affected skin. The ~50 kDa fraction is associated with absorption into the skin and reduction of the appearance of wrinkles.

Ultra-low molecular weight versions (below ~50 kDa) are considered controversial, as research by Evonik suggests that very low molecular weight HA naturally acts as a pro-inflammatory signal molecule in the body; individuals with inflammatory skin conditions should be aware of this distinction.