INCI · peptide · CIR review pending · used in 4 products
Dipeptide-2
Dipeptide-2 is a small synthetic dipeptide composed of two amino acids, valine and tryptophan. It is best known as a component of the patented 3-active complex called Eyeliss, alongside HMC and Palmitoyl Tetrapeptide-7. Its official CosIng function is listed as skin conditioning.
Evidence level
weakEWG score
—Comedogenic
—Category
peptide● Benefits
The manufacturer claims Dipeptide-2 can increase lymphatic circulation, and as part of the Eyeliss complex it is marketed to reduce under-eye puffiness. A manufacturer-conducted clinical study of 20 participants using 3% Eyeliss showed improvement in 70% of participants after 56 days.
anti-puffinesscell-communicatinghydrating
● Cautions
Evidence is limited to a small (n=20), manufacturer-sponsored clinical study; independent, large-scale clinical data are not referenced in the source.



