Ceramide NP (Ceramide 3)
Ceramide NP (also known as Ceramide 3) is an N-acylated sphingolipid consisting of phytosphingosine with the D-erythro structure linked to a normal saturated or unsaturated fatty acid (CAS #72968-43-5). It is one of many ceramide types found naturally in the uppermost layer of the skin. Ceramides collectively make up approximately 50% of the lipid matrix between skin cells, playing a key structural role in the skin barrier. It is classified by CosIng as a hair and skin conditioning ingredient.
Ceramide NP supports a healthy skin barrier and helps keep the skin hydrated by replenishing naturally occurring ceramides in the stratum corneum. Research indicates it acts synergistically with Ceramide 1 (Ceramide AP) to improve skin hydration and reduce transepidermal water loss, particularly on surfactant-irritated skin.
