Berberis Vulgaris Root Extract
Berberis Vulgaris Root Extract is derived from the fresh root bark of the barberry shrub (Berberis vulgaris L., Berberidaceae), a medium-sized shrub known for its edible red berries. It contains alkaloids, most notably berberine, which are responsible for its primary bioactive properties. Various parts of the plant have been used in folk medicine for centuries across multiple cultures. Its CAS numbers are 84649-92-3 / 8054-40-8.
The extract's key alkaloid, berberine, exhibits significant antibacterial and anti-inflammatory properties. An animal study found berberine can reduce lipogenesis in sebaceous glands, suggesting a potential mechanism for its use against acne vulgaris. Traditional Japanese-Chinese herbal medicines containing berberine have shown activity against acne.
