Curi/Atlas/Acetyl Hexapeptide-8

INCI · peptide · CIR review pending · used in 42 products

아세틸헥사펩타이드-8

Acetyl Hexapeptide-8

Acetyl Hexapeptide-8 (also known as Argireline or Acetyl Hexapeptide-3) is a synthetic peptide composed of arginine, methionine, and acetylated glutamic acid residues (CAS #616204-22-9). It is marketed as targeting the same wrinkle-forming mechanism as Botox — specifically wrinkles caused by facial muscle movement — though its mechanism and extent of effect are notably different. It is classified by CosIng as a humectant and skin-conditioning ingredient.

Evidence level

moderate

EWG score

—

Comedogenic

—

Category

peptide

● Benefits

In-vivo studies showed a 10% Argireline solution applied around the eyes for 15 days decreased wrinkle depth by 17%, and a 5% formula applied for 28 days decreased wrinkle depth by 16.26%. Independent university research found it increased skin moisturization and significantly decreased both the depth and width of wrinkles. It is considered a quick-fix for wrinkle smoothing rather than a structural anti-aging treatment like vitamin C, AHAs, or retinol.

anti-aginghydratinganti-wrinkle

● Cautions

The source notes it is not a collagen builder and does not address structural aging; its wrinkle-relaxing effect is considerably less pronounced than Botox injections.

Where Curi finds it.

Curi's featured formulas containing Acetyl Hexapeptide-8.

Mediheal Mediheal AQUHA Rose AHA Skin Tonic

Mediheal · 메디힐

Mediheal AQUHA Rose AHA Skin Tonic

locks in moisturepromotes bright, balanced skin

COSRX Advanced Snail Peptide Eye Cream

COSRX · 코스알엑스

Advanced Snail Peptide Eye Cream

Visibly brightens dark circlesHydrating and lightweight

Mizon Collagen 100

Mizon · 미즌

COSRX COSRX The Peptide Collagen Lifting Glow Hydrogel Mask

COSRX · 코스알엑스

COSRX The Peptide Collagen Lifting Glow Hydrogel Mask

Lifts and firms sagging skinRevitalizes with peptides and collagen

innisfree Black Tea Youth Enhancing Treatment Essence

innisfree · 이니스프리

Black Tea Youth Enhancing Treatment Essence

Antioxidant-rich Black Tea formulaHydrates and promotes cell turnover

More formulas with Acetyl Hexapeptide-8.

42 formulas in cufind's catalog carry Acetyl Hexapeptide-8.

Mediheal Mediheal A:PE Proatin Mask

Mediheal A:PE Proatin Mask

barrier-damageredness

AHC A.H.C Natural Perfection Double Shield Sun Stick

A.H.C Natural Perfection Double Shield Sun Stick

dehydrationredness

Beauty of Joseon Red Bean Water Gel

Beauty of Joseon

Red Bean Water Gel

COSRX COSRX The Blue Peptide Bakuchiol Plump Glow Serum

COSRX The Blue Peptide Bakuchiol Plump Glow Serum

dullnessuneven-tone

COSRX One Step Original Peptide Collagen Lifting Glow Pad

One Step Original Peptide Collagen Lifting Glow Pad

dullnessfine-lines

COSRX The Peptide Collagen Hydrogel Eye Patch

The Peptide Collagen Hydrogel Eye Patch

dark-circlesfine-lines

COSRX COSRX 5 PDRN Collagen Intense Vitalizing Serum

COSRX 5 PDRN Collagen Intense Vitalizing Serum

fine-linesdullness

COSRX COSRX 5 PDRN B5 Vital Soothing Toner

COSRX 5 PDRN B5 Vital Soothing Toner

rednessbarrier-damage

COSRX COSRX PDRN EXOSOME Skinplaning Glaze Mask

COSRX PDRN EXOSOME Skinplaning Glaze Mask

dullnessuneven-tone

COSRX ALL ABOUT SNAIL KIT 4-step

ALL ABOUT SNAIL KIT 4-step

dehydrationdullness

Round Lab Bestselling Sunscreen Duo

Facial Sunscreen & Sun Care

Bestselling Sunscreen Duo

Round Lab Camellia Deep Collagen V Lifting Gel Mask

Camellia Deep Collagen V Lifting Gel Mask

fine-linesdark-circles

MEDICUBE Kojic Acid Turmeric Vita Capsule Cream

Kojic Acid Turmeric Vita Capsule Cream

dullnessuneven-tone

MEDICUBE [Subscr.] Hyaluronic Multi Peptide PDRN Serum

[Subscr.] Hyaluronic Multi Peptide PDRN Serum

dehydrationuneven-tone

MEDICUBE [Subscr.] No Cast Just Glow Collagen Sunscreen

[Subscr.] No Cast Just Glow Collagen Sunscreen

MEDICUBE [Subscr.] PDRN Pink Peptide Serum

[Subscr.] PDRN Pink Peptide Serum

MEDICUBE [Subscr.] Salmon PDRN Pink Collagen Jelly Gel Mask

[Subscr.] Salmon PDRN Pink Collagen Jelly Gel Mask

MEDICUBE [Subscr.] PDRN Pink Collagen Capsule Cream

[Subscr.] PDRN Pink Collagen Capsule Cream

uneven-tonebreakouts

MEDICUBE [Subscr.] PDRN Pink Peptide Toner

[Subscr.] PDRN Pink Peptide Toner

dullnessuneven-tone

MEDICUBE [Subscr.] PDRN Pink Peptide Eye Cream

[Subscr.] PDRN Pink Peptide Eye Cream

fine-linesdark-circles

MEDICUBE Kojic Acid Turmeric Capsule Serum

Kojic Acid Turmeric Capsule Serum

MEDICUBE PDRN Pink Caffeine Overnight Wrapping Mask

PDRN Pink Caffeine Overnight Wrapping Mask

MEDICUBE Hyaluronic Multi Peptide PDRN Serum

Hyaluronic Multi Peptide PDRN Serum

dehydrationuneven-tone

MEDICUBE Retinol NMN Boosting Serum

Retinol NMN Boosting Serum

fine-linesuneven-tone

MEDICUBE PDRN Lip Sleeping Mask

PDRN Lip Sleeping Mask

MEDICUBE PDRN Pink Peptide Eye Cream

PDRN Pink Peptide Eye Cream

fine-linesdark-circles

Sulwhasoo Concentrated Ginseng Rejuvenating Eye Cream Set

Concentrated Ginseng Rejuvenating Eye Cream Set

fine-linesdark-circles

Klairs Vitamin PDRN Bouncy Pore Serum

Vitamin PDRN Bouncy Pore Serum

Klairs Maple Energy Infusing Serum

Maple Energy Infusing Serum

Klairs Maple Energy Infusing Cream

Maple Energy Infusing Cream

Klairs Fundamental Watery Oil Drop

Fundamental Watery Oil Drop

Klairs Fundamental Eye Awakening Gel

Fundamental Eye Awakening Gel

Klairs Fundamental Nourishing Eye Butter

Fundamental Nourishing Eye Butter

Klairs Gentle Black Facial Cleanser

Gentle Black Facial Cleanser

Mizon Black Snail All in One Cream

Black Snail All in One Cream

Mizon Snail Recovery Gel Cream

Snail Recovery Gel Cream

Mizon Cicaluronic Vegan De-Puffing Eye Gel Patch

Cicaluronic Vegan De-Puffing Eye Gel Patch